Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTT-N--VQLLREPETAESFHDTPTLYGIPILFP-PNRISDGTFSFRGRTYHFDINEKDKHNHLHGF---LYHEKWNVVTTKQTDEGVIVETEIDLSELPHVQKQFPHHAVVRMTYTIKE-NTLFKHATVMNKGKEAFPWGIGYHTTFIFPA----ESSLFSLTADQQWELDERLLPTGKLMDVPYK-EALHEGMDLRH--------KQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEQFKHWVVYNADG------------KQGYLCPEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ 1LUR Chain:A ((14-337)) -------------FIEIANKQGLTATLLP-FGATLAKLTFPDKNGKNQDLVLGFDTIDEFE-KDAASIGKTVGRVANRIKNSTLHFDGKQYTMTPNN--GPHYLHGGPNGLGYRKWEVVRHAP----ESVSFSVRANE---QDDGLPGDAKIDVTYTVNDRNQLIIEHHAT--CDTPGLLALTNHAYWNLDGSDTVAEHFLEMEADEFVEVDDTFCPTGAIRSVTDTGFDFRSGKQLKESGKDAEELLDLDNDLVITK--KTPSTYLRFWSEKSGIELSIT--TSYPVIHLYASKFLDCKGKKGEHYKANKALAIEPQFH-SAAPNFDH----FPDVSLRPGDHYCQEIVYTFSH---

General information: TITO was launched using: RESULT: Template: 1LUR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1658 4825 2.91 16.81 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : 2.91 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.404

(partial model without unconserved sides chains): PDB file : Tito_1LUR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LUR-query.scw PDB file : Tito_Scwrl_1LUR.pdb: