Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MVSIRRSFEAYVDDMNIITVLIPAEQKEIMTPPFRLETEITDFPLAVREEYSLEAKYKYVCVSDHPVTFGKIHCVRASSGHKTDLQIGAVIRTAAFDDEFYYDGELGAVYTAD--HTVFKVWAPAATSAAVKLS---HPNKSGRTFQMTRLEKGVYAVTVTGD-----LHGYEYLFCICNNSEWMETVDQYAKAVT----------VNGEKGVVLRPDQMK----WTAPLKPFSHPVDAVIYETHLRDFSIHENSGMINKGKYLALTETDTQTANGSSSGLAYVKELGVTHVELLPVNDFAGVDEEKP---------LDAYNWGYNPLHFFAPEGSYASNPHDPQTRKTELKQMINTLHQHGLRVILDVVFNHVYKRENSPFEKTVPGYFFRHDECGMPSNGTGVGNDIASERRMARKFIADCVVYWLEEYNVDGFRFDLLGILDIDTVLYMKEKATKAKPGILLFGEGWDLAT--PLPHEQKAALANAPRMPGIGFFNDMFRDAVKGNTFHLKATGFALGNGESAQAVMHGIAGSSGWKALAPIVPEPSQSINYVESHDNHTFWDKMSFAL---PQENDSRKRSRQRLAAAIILLAQGVPFIHSGQEFFRTKQG------------------------------VENSYQSSDSINQLDWDRR------ETFKEDVHYIRRLISLRKAHPAFRLRSAADIQRHLECLTL--------KEHLIAYRLYDLDEVDEWKDIIVIHHASPDSVEWRLPNDI----PYRLLCDPSGFQEDPTEIKKTVAVNGIGTVILYLASDLKSFA 3FAW Chain:A ((37-814)) ---QVQLKDAQQTDLTSIQASFTTLDKTEILKELKVTD--KNQNAIQISDITLDTSKSLLIIKGDFNPKQGHFNISYN-----GNNVTTRQSWEFKDQLYAYSGNLGAVLNQDGSKVEASLWSPSADSVTMIIYDKDNQNRVVATTPLVKNNKGVWQTILDTKLGIKNYTGYYYLYEIKRGKDKVKILDPYAKSLAEWDSNTVNDDIKTAKAAFVNPSQLGPQNLSFAKIANFKGRQDAVIYEAHVRDFTSDQSLD--------GKLKNQLGTFAAFSEKLDYLQKLGVTHIQLLPVLSYFYVNEMDKSRSTAYTSSDNNYNWGYDPQSYFALSGMYSEKPKDPSARIAELKQLIHDIHKRGMGVILDVVYNHTAK--TYLFEDIEPNYYHFMNEDGSPRESFG-GGRLGTTHAMSRRVLVDSIKYLTSEFKVDGFRFDMMGDHDAAAIELAYKEAKAINPNMIMIGEGWRTFQGDQGKPVKPADQDWMKSTDTVGVFSDDIRNSLKSGFPNEGTPAFITGGPQSLQGIFKNIKAQPG----NFEADSPGDVVQYIAAHDNLTLHDVIAKSINKDPKVAEEDIHRRLRLGNVMILTSQGTAFIHSGQEYGRTKRLLNPDYMTKVSDDKLPNKATLIEAVKEYPYFIHDSYDSSDAINHFDWAAATDNNKHPISTKTQAYTAGLITLRRSTDAFRKLSKAEIDREVSLITEVGQGDIKEKDLVIAYQTID----SKGDIYAVFVNADSKARNVLLGEKYKHLLKGQVIVDADQAGIKPISTPRGVHFEKDSLLIDPLTAIVIKVG

General information: TITO was launched using: RESULT: Template: 3FAW.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 4166 10624 2.55 15.42 target 2D structure prediction score : 0.63 Monomeric hydrophicity matching model chain A : 0.73 3D Compatibility (PKB) : 2.55 2D Compatibility (Sec. Struct. Predict.) : 0.63 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.389

(partial model without unconserved sides chains): PDB file : Tito_3FAW.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3FAW-query.scw PDB file : Tito_Scwrl_3FAW.pdb: