Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKMLLFLIIAAVSMLTIAGCSSQSSSADGKVTLKFFHRWPKEPEKSYFEEVVKEFEKDHPDIDIQIEAVLNDSYKDKIKVMLGTTSPPDIYFSWSDEFAFKFIRGNKALDLSSYYKNDTDWSSQLVQSQITPFTYENKQYGVPWQMDAKSFFYNKDIFQKLNLD---PPKTWDELIDVSKKLKEHG--YTPISFGTKATWTISHYIGTLNQRMVDEKTREKDYNAKTGEFTDEGYVKALEKLQELM--PYFNKHVNSVDHEYVRQQFKSGKSAMIYAETAEI-KLVE-----PVNLGMFPFPEISGQKGSSEALTGAPEGFMISSRTKHPKEAMEFLQFLTSKRMGEKLVKD-VGKYSAVQGTATE-E-NATAIQREAVQHIVDAKSMVPWFDMDVDVEVADAYLTGVQQMLGGDMTPQQVMKAVQKAAKQVRASAE 5CI5 Chain:A ((22-414)) ------------------------------SKTLTIWIGGQVAELDETWNSVIKTFEEKY-GISVEVQLFGFDTYYDKLVTALQAGKGPDLAFADLGGWVPTFAEKGWLEPMEEHLKNWEGT-AQIWPNLWPTVTYKKIRYGLPWYTDCRLLLYNKAMFEKAGLNPDNPPKTWDELLDAALKITDTKNRIYGYGVSGTKTEHTTLGYMMF-LYAAGGKLLTDD-YSK-AAFDSPEGLKALKFYTDLAKKYNVSPNAIQYHEDDYRNMMAQNRVAMAIGGPWSFPLIEAANPDIAGKYSVALHPYDAKPA---SVLG--GWALVIPSSSPNKEDAWKLAEYLTSFDVWMKWVEEKGGPMPTRMDVCKKSKLANDVKWQIIFETFPHAVARP-P--IPQYPQISEQIQTMVQRVLLGELTPEEAIKIAAENVNKILGA--

General information: TITO was launched using: RESULT: Template: 5CI5.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2192 -29662 -13.53 -78.68 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -13.53 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.430

(partial model without unconserved sides chains): PDB file : Tito_5CI5.pdb: (Unconserved sides chains are recalculated) : Sequence: align-5CI5-query.scw PDB file : Tito_Scwrl_5CI5.pdb: