Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKIAVIGTGYVGLVSGTCFAEIGNKVVCCDIDESKIRSLKNGVIPIYEPGLADLVEKNVLDQRLTFTNDIPSAIRASDIIYIAVGTPMSKTGEADLTYVKAAAKTIGEHLNGYKVIVNKSTVPVGTGKLVQSIVQK---ASKGRYSFDVVSNPEFLREGSAIHDTMNMERAVIGSTS----HKAAAIIEELHQPF---HAPVIKTNLESAEMIKYAANAFLATKISFINDIANICERVGADVSKVADGVGLDSRIGRKFLKAGIGFGGSCFPKDTTALLQIAKSAGYPFKLIEAVIETNEKQRVHIVDKLLTVMG-SVKGRTISVLGLAFKPNTNDVRSAPALDIIPMLQQLGAHVKAYDPIAIPEASAILG----------EQVEYYTDVYAAMEDTDACLILTDWPEVKEMELVKVKTLLKQPVIIDGRNLFSLEEMQAAGYIYHSIGRPAVRGTEPSDKYFPGLPLEELAKDLGSVNL 2Y0D Chain:B ((11-461)) ---LTIIGSGKVGLVTGACLADIGHDVFCLDVDQAKIDILNNGGVPIHEPGLKEVIARNRSAGRLRFSTDIEAAVAHGDVQFIAVGTP-----SADLQYVLAAARNIGRYMTGFKVIVDKSTVPVGTAERVRAAVAEELAKRGG-QMFSVVSNPEFLKEGAAVDDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGADIEAVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGQSLQILKAVSSVNATQKRVLADKIVARFGEDLTGRTFAIWGLAFKPNTDDMREAPSRELIAELLSRGARIAAYDPVAQEEARRVIALDLADHPSWLERLSFVDDEAQAARDADALVIVTEWKIFKSPDFVALGRLWKTPVIFDGRNLYEPETMSEQGIEYHPIGRPG----------------------------

General information: TITO was launched using: RESULT: Template: 2Y0D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2248 -84331 -37.51 -198.89 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain B : 0.81 3D Compatibility (PKB) : -37.51 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.81 QMean score : 0.591

(partial model without unconserved sides chains): PDB file : Tito_2Y0D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2Y0D-query.scw PDB file : Tito_Scwrl_2Y0D.pdb: