Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKAVSVILTLSLFLLTACSLEPPQWAKPSNSGNKKEFTIGLSVSTLNNPFFVSLKKGIEKEAKKRGMKVIIVDAQNDSSKQTSDVEDLIQQGVDALLINPTDSSAISTAVESANAVGVPVVTIDRSAE-QGKVETLVASDNVKGGEMAAAFIADKLG-KGAKVAELEGVPGASATRERGSG---------FHNIADQKLQVVTKQSADFDRTKGLTVMENLLQGHPDIQAVFAHNDEMALGALEAINSSGKD--ILVIGFDGNKDALASIKDRKLSATVAQQPELIGKLATEAADDILHG--KKVQK-TISAPLKLETQK 4RY9 Chain:A ((8-284)) -------------------------------------FKIGVSMKTLSAPYFAAQMEAAKARGKELGYEVLATDAQGKLQKQISDVEDLVTRGVKLLIINPADSEGLVNAVNNASANGVKVVVIDSTLNPRANFVTQVQSSNSINGALVGHWVIEEVGNKSLKIALLSGEKGNPVGQERRLGVLSGIIEAQLRKFGKADLTVVGQGWGHWNDEGGLKAMEDLLVANKDINMVLGENDSMVLGARRAIESAGRTGILLVAAADAQKEALALIKQGKYGVTGLNDPALVARTAIDLGVKVVKGEVKDVPKQTLTTP-------

General information: TITO was launched using: RESULT: Template: 4RY9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1530 16653 10.88 63.80 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.77 3D Compatibility (PKB) : 10.88 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.77 QMean score : 0.571

(partial model without unconserved sides chains): PDB file : Tito_4RY9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4RY9-query.scw PDB file : Tito_Scwrl_4RY9.pdb: