Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPSFDVVFVGHRR-GEVRSDNAMLGLLCDAAFDEL--TRPDVVIFPGGIGTR-TLIHDQTVLDWVREAHRHTLLTTSVCTGGLVLAAAGLLNGLTATTHWRVQDLF-NSLGARYVPQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAAEASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL 4E08 Chain:A ((32-189)) --GIKVTVAGLNGGEAVKCS-RDVQILPDTSLAQVASDKFDVVVLPGGLGGSNAMGESSLVGDLLRSQESGGGLIAAICAAPTVLAKHGVASGKSLTSYPSMKPQLVNNYSYV-DDKTVVK--DGNLITSRGPGTAYEFALKIAEELAGKEKVQEVAKGLLVAY----------------------------

General information: TITO was launched using: RESULT: Template: 4E08.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -98386 for 1161 contacts (-84.7/contact) + 2D Compatibility (PS) -16804 + (NN) -8680 + (LL) 2164 1D Compatibility (HY) -7600 + (ID) 1650 Total energy: -130956.0 ( -112.80 by residue) QMean score : 0.442

(partial model without unconserved sides chains): PDB file : Tito_4E08.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4E08-query.scw PDB file : Tito_Scwrl_4E08.pdb: