Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTSYMLGIDIGTTSTKAVLFSENGDVVQKESIGYPLYTPDISTAEQNPEEIFQAVIHTTARITKQH--PEKRISFISFSSAMHSVIAIDENDKPLT---------PCITWADNRSEGWAHKIKEELNGHEVYKRTGTPIHPMAPLSKIAWITNERKEIASKAKKYIGIKEYIFKQLFNEYVIDYSLASATGMMNLKGLDWDEEALRIAGITP------DHLS-KLVPTTEIFQH-CSPEIAIQMGIDPETPFVIGASDGVLSNLGV----NAIKK-----GEIAVTIGTSGAIRTIIDKPQTDEKGR--I-FCYALTDKHWVIGGPVNNGGIVLRWIRDEFASSEIET--ATRLGIDPYDVLTKIAQR-------VRPGSDGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIR---AALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSEVWRQMMSDIFESEVVVPESYESSCLGACILGLYATGKIDSFDAVS-DMIGSTYRHTPIEDS-AKEYRTLMPIFINLSRLLENQYTQIADYQRGLITHK 3L0Q Chain:A ((4-544)) -ASYFIGVDVGTGSARAGVFDLQGRMVGQASREITMFKPKADFVEQSSENIWQAVCNAVRDAVNQADINPIQVKGLGFDAT-CSLVVLDKEGNPLTVSPSGRNEQNVIVWMDHRAITQAERINATK--HPVLEFVGGVISPEMQTPKLLWLKQHMPNTWSNVGHLFDLPDFLTWRATKDETRSLCSTVCKWTYLGHEDRWDPSYFKLVGLADLLDNNAAKIGATVKPMGAPLGHGLSQRAASEMGLIPGTAVSVSIIDAHAGTIGILGASGVTGENANFDRRIALIGGTSTAHMAMSRSAHFIS-GIWGPYYSAI-LPEYWLNEGGQSATGALIDHIIQSHPCYPALLEQAKNKGETIYEALNYILRQMAGEPENIAFLTNDIHMLPYFHGNRSPRANPNLTGIITGLKLSTTPEDMALRYLATIQALALGTRHIIETMNQN-GYNIDTMMASGGGTKNPIFVQEHANATGCAMLLPEESEAMLLGSAMMGTVAAGVFESLPEAMAAMSRIGKTVTPQTNKIKAYYDRKYRVFHQMYHDHMRYQ-ALMQ---------

General information: TITO was launched using: RESULT: Template: 3L0Q.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3230 -37394 -11.58 -75.39 target 2D structure prediction score : 0.61 Monomeric hydrophicity matching model chain A : 0.70 3D Compatibility (PKB) : -11.58 2D Compatibility (Sec. Struct. Predict.) : 0.61 1D Compatibility (Hydrophobicity) : 0.70 QMean score : 0.511

(partial model without unconserved sides chains): PDB file : Tito_3L0Q.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3L0Q-query.scw PDB file : Tito_Scwrl_3L0Q.pdb: