Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDRLPRIPLADIIDRFVDWITMTFGGFFDGIANGLAAFVNGIVTGLGFIPSILLTIIFAALAWWISTRGIALFTLIGFLLIDYLGYWDPMLQTLALVLTSVIISIVVGVPIGIWASQKE-TVRRIVTPILDLMQTMPAFVYLLPAIFFFNIG--------------VVPGVVASVIFAMPPTIRMTVLGIKQVPADLIEATEAFGSTTAQRLFKVQLPLATKTILAGINQSIMLALSMVVIAAMVGA--PGLGSEVYSAVTQLKTGVGVEAGIAIVIVAITLDRITQNIKVKKKSRGNA 2ONK Chain:C ((66-275)) ---------------------------------------------------------------------------------SDPAVWKVVLTTYYAALISTLIAVIFGTPLAYILARKSFPGKSVVEGIVDLPVVIPHTVAGIALLVVFGSSGLIGSFSPLKFVDALPGIVVAMLFVSVPIYINQAKEGFASVDVRLEHVARTLGSSPLRVFFTVSLPLSVRHIVAGAIMSWARGISEFGAVVVIAYYPMIAPTLIYERYLSEGLSAAMPVAAILILLSLAVFVALRIIVG--------

General information: TITO was launched using: RESULT: Template: 2ONK.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 752 -131583 -174.98 -681.78 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain C : 0.61 3D Compatibility (PKB) : -174.98 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.321

(partial model without unconserved sides chains): PDB file : Tito_2ONK.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ONK-query.scw PDB file : Tito_Scwrl_2ONK.pdb: