Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLKELFVNLTILITFNYLFTHLFKERLVHKKDSISFQAVKGLACGLLGVILMVFGFTYQHSIIDLRNIPIMIAALYGGWVSTATALAMITAGRLLITMNTSALYSVIIICIAAIPSLIVSRRKKVQLKHAFYLLIITNSLISFSFYFLIDLHSYELHLYFWIISIAGGMLSLYIIDHETNAHLLFKQYKFQAHFDFLTGVYNRRKFEETTKALYQQAADTPHFQFALIYMDIDHFKTINDQYGHHEGDQVLKELGLRLKQTI-RNTDPAARIGGEEFAVLLPNCSLDKAARIAERIRSTVS------DAPIVLTNGDELSVTISLGAAHYPNNTEQPGSLPI-LADQMLYKAKETGRNRVCFSEKKE 3I5C Chain:B ((33-198)) --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGLTGLSNRRHFDEYLEMEWRRSLRE-QSQLSLLMIDVDYFKSYNDTFGHVAGDEALRQVAGAIREGCSRSSDLAARYGGEEFAMVLPGTSPGGARLLAEKVRRTVESLQISHDQP---RPGSHLTVSIGV-STLVPGGGGQTFRVLIEMADQALYQAKNNGRNQVGLMEQ--

General information: TITO was launched using: RESULT: Template: 3I5C.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 777 -88010 -113.27 -557.02 target 2D structure prediction score : 0.76 Monomeric hydrophicity matching model chain B : 0.58 3D Compatibility (PKB) : -113.27 2D Compatibility (Sec. Struct. Predict.) : 0.76 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.577

(partial model without unconserved sides chains): PDB file : Tito_3I5C.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3I5C-query.scw PDB file : Tito_Scwrl_3I5C.pdb: