Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKMSLFQNMKSKLLPIAAVSVLTAGIFAGAELQQTEKASAKKQDKAEIRNVIVMIGDGMGTPYIRAYRSMKNNGDTPNNPKL--------TEFDR-NLTGMMMTHPDDPDYNITDSAAAGTALATGVKTYNNAIG-VDKNG---KKVKSVLEEAKQQGKSTGLVATSEINHATPAAYGAHNESRKNMDQIANSYMDDKIKGKHKIDVLLGGGKSYFNRKDRN---LTKEFKQAGYSYVTTKQALKKNKDQQVLGLFA-DGGLAKALDR----DSKTPSLKDMTVSAIDRLNQ--NKKGFFLMVEGSQIDWAAHDNDTVGAMSEVKDFEQAYKAAIEFAKKD-KHTLVIATADHTTGGFTIGANGEKNWHAEPILSAKKTPEFMAKKISEGKPVKDVLARYANLKVTSEEIKSVEAAAQADKSKGASKAIIKIFNTRSNSGWTSTDHTGEEVPVYAYGPGKEKFRGLINNTDQANIIFKILKTGK 2X98 Chain:B ((6-416)) --------------------------------------------------NAIAYIVDGMGQTQISAARYLNAYKTAPERFPLNVSPAETPTGFDAFSSRGSMTTFPDDPYETTTDSAAAATAFASGVKTYNGAIGGVQTSGGGFQRVDTVLERASAQGYATGLITTTEATHATPAAFAAHVEDRGNQTEIARQYIEET-----QPDVILGGQRRDFEADASNGGTLVDAARDNGYTIAETAAELDAVDDPPVLGLFSQESHLDYYLDRKNDPENTQPNLDAMVDAGVDLLS-GDPDKGFFLLVESGRVDHAGHAN-YPAQVAEQYEATQVAGQLVEYAETTAEPTFLVSTGDHECGGLTLGRDSPYEVEYD-VLAAQKATTSRLRDLLAGVRSADELESIVAAHTGITALTDREVA----KLRDAPGSISTILAERAGIAFTTDGHTGTDVPVFAHGPNAARFDAARDNT--------------

General information: TITO was launched using: RESULT: Template: 2X98.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 2417 -91237 -37.75 -236.98 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain B : 0.74 3D Compatibility (PKB) : -37.75 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.496

(partial model without unconserved sides chains): PDB file : Tito_2X98.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2X98-query.scw PDB file : Tito_Scwrl_2X98.pdb: