Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLEVKTISVEDTYEIRHRI---LRPHQSIE-QCKYKEDHAEGSFHLGVFYDGTLISIASFSPQSQPLLTEASAYRLRGMATLEGYRDQKAGSTLIKHAEHKLAESG-VQAVWCNA---RHHVKGYYAKLGWKELGEPFDI--PGI-GNHIVMYKTLRTSR 2OB0 Chain:A ((7-155)) -IELGDVTPHNIKQLKRLNQVIFPVSYNDKFYKDVLE---VGELAKLAYFNDIAVGAVCCRVDHSQ---NQKRLYIMTLGCLAPYRRLGIGTKMLNHVLNICEKDGTFDNIYLHVQISNESAIDFYRKFGFEIIETKKNYYKRIEPADAHVLQKNL----

General information: TITO was launched using: RESULT: Template: 2OB0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 609 -90930 -149.31 -658.91 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : -149.31 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.454

(partial model without unconserved sides chains): PDB file : Tito_2OB0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2OB0-query.scw PDB file : Tito_Scwrl_2OB0.pdb: