Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKTCF-LSIWRVVDPI-YFFFSRLSLIDNDQKSVFRVRLTKYKGHHVVL-SDGTHIR-KNDV-LVKIHLHNIKLIRELQSIESAVRKGIIIYQKVYQSMPLLLDYINNHKK-SEKIKGIIGITMLDKG-VERLGFDVITPVNPFYRCFKKVSHVPILYLTSKPVSLRHLPNSSYLFISKEKLQKTY-QKKD 4NOH Chain:A ((3-169)) ATGIVMYGDETGVQQTMDQYKDK-----IESQNKFEAKLGTVNEKKVLIMNKTTAEKMVKENMLKKVVKEDVEPIKALPAISD--EAGIVFAKEEQKDVVI------DGKKMKYEGNVVIGDARKYTDMY------AVVSDAEYAKISEPVKTIGLASFKENPK-----EKIFPDIKRGSKVEEAHMVEVK

General information: TITO was launched using: RESULT: Template: 4NOH.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 789 -49701 -62.99 -312.58 target 2D structure prediction score : 0.33 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -62.99 2D Compatibility (Sec. Struct. Predict.) : 0.33 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.193

(partial model without unconserved sides chains): PDB file : Tito_4NOH.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4NOH-query.scw PDB file : Tito_Scwrl_4NOH.pdb: