Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MRSFATQQNGIFKSVCSLDCP--DQCGLLIHKKDGKIVKVQGDPDHPVT-------AGNICNKVRNMTERIYDEKRLTTPLKRTGAKGQAIFEPISWKEAIDTITSRWKQLIDEEGAESILPYSF-----YGNMGKLTAEGMDRRFFYRMGSSQLERTICSKAGSEGYKYTMG-ISAGIDPEETVHTKLFIFWGINAVSTNMHQITIAQKARKKGAKIVVIDVHKNQTGRLADWFIPIKPGTDSALALGIMHILFKENLHDEAFLSEYTV----------------------------------------------------------------------GYEELREHVKQYDPEKVSTITGVSTEDIYRLAKMYGETSPSFIRIGNGPQHHDNGGMIVRTIACLPAITGQWLHTGGGAIKHNS------------GIL-EYNTN-AL------------QRPDLLK--G--R-------TPRSFN----------MN------QLG------------RV-L-----------LETDPPIRSLFIYGTNPAVVAPEANKVRQ--GLLREDLFTVVHDLFLTETAAYADIVLPATSAFENTDFYTSYW-HHYIQLQQPVIERYGESKSNTEVFRLLAEAMGFTD-------QELK-------D-------------SDEVLIRQALDH-PDN-PHLAEIDYDSLTKHSFM-KAKRE---------------KPL--------FPGELPTPSGKIELYSEKMK-QDGFPALPTYTPLVT-DNEHPFMYVPGPNHNFLNSTFSNNEKHIKLEKT-PKLFINTKDAEKHGIVDGAPVRIWNSRGECELTAAVGEQVLPGVVVSQGLWADEQGKKQLVNALTPDRLSD---MGGGA--------------TFFSGRVQIEKV 2IVF Chain:A ((80-976)) ------------GSHLN-ICWPQGSCKFYVYVRNGIVWREEQAAQTPACNVDYVDYNPLGCQKGSAFNNNLYGDERVKYPLKRVGKRGEGKWKRVSWDEAAGDIADSIIDSFEAQGSDGFILDAPHVHAGSIAWGAGF---RMTYLMDGVS-PDI--NVDIGDTYMGAFHTFGKMHMGYSADNLLDAELIFMTCSNWSYTYPSSYHFLSEARYKGAEVVVIAPDFNPTTPAADLHVPVRVGSDAAFWLGLSQVMIDEKLFDRQFVCEQTDLPLLVRMDTGKFLSAEDVDGGEAKQFYFFDEKAGSVRKASRGTLKLDFMPALEGTFSARLKNGKTIQVRTVFEGLREHLKDYTPEKASAKCGVPVSLIRELGRKVAKK-RTCSYIGFSSAKSYHGDLMERSLFLAMALSGNWGKPGTGAFAWAYSDDNMVYLGVMSKPTAQGGMDELHQMAEGFNKRTLEADPTSTDEMGNIEFMKVVTSAVGLVPPAMWLYYHVGYDQLWNNKAWTDPALKKSFGAYLDEAKEKGWWTNDHIRPAPDKTPQVYMLLSQNPMRRKRSGAK-MFPDVLFPKLKMIFALETRMSSSAMYADIVLPCAWYYEKHEMTTPCSGNPFFTFVDRSVAPPGECREEWDAIALILKKVGERAAARGLTEFNDHNGRKRRYDELYKKFTMDGHLLTNEDCLKEMVDINRAVGVFAKDYTYEKFKKEGQTRFLSMGTGVSRYAHANEVDVTKPIYPMRWHFDDKKVFPTHTRRAQFYLDHDWYLEAGESLPTHKDTPMVGGDHPFKITGGHPRVSIHSTHLTNSHLSRLHRGQPVVHMNSKDAAELGIKDGDMAKLFNDFADCEIMVRTAPNVQPKQCIVYFWDAHQYKGWKPYDILLIGMPKPLHLAGGYEQFRYYFMNGSPAPVTDRGVRVSIKKA

General information: TITO was launched using: RESULT: Template: 2IVF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 3708 99746 26.90 151.36 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.66 3D Compatibility (PKB) : 26.90 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.469

(partial model without unconserved sides chains): PDB file : Tito_2IVF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IVF-query.scw PDB file : Tito_Scwrl_2IVF.pdb: