Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTLIILEGPDCCFKSTVAAKLSKELKY--P--IIKGSSFE--LAKSG--------NE----KL-FE--HF--------NKLADEDNVIIDRFVYSNLVYAKKFKDYSILTERQLRFIE--DKIKAKAK-VVYLHADPSVIKKRLRVRGDEYIE-----GKDIDSILELYREVMSNAGLHTYSWDTGQWSSDEIAKDIIFLVE 4HLC Chain:A ((2-198)) SAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTGEEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQGYA--RGI-GVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIK-------LDQEDLKFHEKVIEGYQEIIHNESQRFKSVNADQ-PLENVVEDTYQTI-

General information: TITO was launched using: RESULT: Template: 4HLC.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 625 10271 16.43 67.13 target 2D structure prediction score : 0.67 Monomeric hydrophicity matching model chain A : 0.67 3D Compatibility (PKB) : 16.43 2D Compatibility (Sec. Struct. Predict.) : 0.67 1D Compatibility (Hydrophobicity) : 0.67 QMean score : 0.525

(partial model without unconserved sides chains): PDB file : Tito_4HLC.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HLC-query.scw PDB file : Tito_Scwrl_4HLC.pdb: