Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MNKTELIAKVAEKQG-VSKKEGAPSVEKVFDTISEALKSGEKVSIPGFGTFEVRERAARKGRNPQTGEEIDIPATKAPAFKPAKALKDAVKAK 1OWF Chain:B ((1-88)) MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIAIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRD-----

General information: TITO was launched using: RESULT: Template: 1OWF.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 183 18343 100.23 210.84 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain B : 0.85 3D Compatibility (PKB) : 100.23 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.85 QMean score : 0.615

(partial model without unconserved sides chains): PDB file : Tito_1OWF.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1OWF-query.scw PDB file : Tito_Scwrl_1OWF.pdb: