Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKIALIAHDKKKQDMVQFTTAYRDILKNHDLYATGTTGLKIHEATGLQIERFQSGPLGGDQQIGALIAANALDLVIFLRDPLTAQPHEPDVSALIRLCDVYSIPLATNMGTAEILVRTLDEGVFEFRDLLRGEEPNV 1IK4 Chain:D ((14-129)) --IALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQS-------------------

General information: TITO was launched using: RESULT: Template: 1IK4.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 550 -104270 -189.58 -898.88 target 2D structure prediction score : 0.71 Monomeric hydrophicity matching model chain D : 0.82 3D Compatibility (PKB) : -189.58 2D Compatibility (Sec. Struct. Predict.) : 0.71 1D Compatibility (Hydrophobicity) : 0.82 QMean score : 0.392

(partial model without unconserved sides chains): PDB file : Tito_1IK4.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IK4-query.scw PDB file : Tito_Scwrl_1IK4.pdb: