Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKLKKRVSMFLVALTMCGGLFVTPAKAVKTTNYAEEIAALQPGTTPEEIMKSASQIAKQQHVKQDVILKQFYKEITADKAEGDRLAKESGMSIMGGSSGTKKLPTSAKGNIYYTNSYT---------AYYNHGHVGMYSAAD---KIVESVPSDGVRQIAYNARDVED---NSIVQTVS--VSSSQKTAAADWAVSKVGDPYSFNFVNNRNTGHDGAKNCSKLLWSAFLLKAGIDIDS---------------------------NGGLGVYPRDITSSSYTTTIMTIY 2IF6 Chain:A ((3-181)) -------------------------------------------------------------------------------------------------------WQPQTGDIIFQISRSSQSKAIQLATHSDYSHTGMLVMRNKKPYVFEAVG--PVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQKLAQTAKRYLGKPYDFSFSWS-----DDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLVQAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEW

General information: TITO was launched using: RESULT: Template: 2IF6.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 597 2210 3.70 16.37 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : 3.70 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.284

(partial model without unconserved sides chains): PDB file : Tito_2IF6.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2IF6-query.scw PDB file : Tito_Scwrl_2IF6.pdb: