Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSKPPAPNPTPPRNLDSRTFITI-GDRNFEVEADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDCFYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLD-KNMTIPEDILGEIAVSIVRALEHLHSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPELNQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPAD---RFSPEFVDFTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS 3ALN Chain:A ((5-310)) ----------------SSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKPSGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREGDCWICMELMSTSFDKFYKYVYSVLDDVIPEEILGKITLATVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLCDFGISGQ------------------------------YDVRSDVWSLGITLYELATGRFPYPKW-------TQVVKGDPPQLSNSEEREFSPSFINFVNLCLTKDESKRPKYKELLKHPFILMYEERAVEVACYVCKILDQM-

General information: TITO was launched using: RESULT: Template: 3ALN.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -184421 for 1996 contacts (-92.4/contact) + 2D Compatibility (PS) -27922 + (NN) -9762 + (LL) 1404 1D Compatibility (HY) -32000 + (ID) 7000 Total energy: -259701.0 ( -130.11 by residue) QMean score : 0.406

(partial model without unconserved sides chains): PDB file : Tito_3ALN.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3ALN-query.scw PDB file : Tito_Scwrl_3ALN.pdb: