Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTKKRITFGLLVLMVCVILFVLYVQLRNKDSIPVQSSAIHPEEDRIFFIYSNPFIKESVLLSTSTGERFNRRTFKVADVPYIQTKSYASTDLVLLAEHEPFYYTLEKDVIKEHPLSDPFAFWYEGKDVTIEAYNVDTTGNEIHINDRKTKKEYTLTLPPLVTMGASDENFIYIIQSM-------SIYVIDRKTEEMIETLS-------LASYADQFADSEEFIVASS--DHKLTVIEKGTWKT-TYIAYPEDLEYADTVYYDKESGSFYVAYEDKEGGANLLEYGEDF-SI-HTYSLKFP------YMEAKFKGNLLYIVAQEEHKKGIGGYVGVFDIHSKEMLYQFDLPEEQVKVQDFVVVDNK 3DSM Chain:A ((2-171)) ------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGLFITNEGNFQYSNATLSYYDPATCEVENEVFYRANGFKLGDVAQSMVIRDGIGWIVVNNSHVIFAIDINTFKEVGRITGFT---SPRYIHFLSD-EKAYVTQIWD---YRIFIINPKTYEITGYIECPDMDMESGSTEQMVQYGKYVYVNCWS-----YQNRILKIDTETDKVVDELTIG---------------

General information: TITO was launched using: RESULT: Template: 3DSM.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 718 -107035 -149.07 -738.17 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.57 3D Compatibility (PKB) : -149.07 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.57 QMean score : 0.452

(partial model without unconserved sides chains): PDB file : Tito_3DSM.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3DSM-query.scw PDB file : Tito_Scwrl_3DSM.pdb: