Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSNEDMEQDNTTLLTEFVLTGLTYQPEWKMPLFLVFLVIYLITIVWNLGLIALIWNDPQLHIPMYFFLGSLAFVDAWISSTVTPKMLVNFLAKNRMISLSECMIQFFSFAFGGTTECFLLATMAYDRYVAICKPLLYPVIMNNSLCIRLLAFSFLGGFLHALIHEVLIFRLTFCNSNIIHHFYCDIIPLFMISCTDPSINFLMVFILSGSIQVFTIVTVLNSYTFALFTILKKKSV--------RGVRKAFSTCGAHLLSVSLYYGPLIFMYLRPASPQ---ADDQDMIDSVFYTIIIPLLNPIIYSLRNKQVIDSFTKMVKRNV 1U19 Chain:A ((40-325)) ----------------------------FSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRF-GENHAIMGVAFTWVMALACAAPPLVGWSR----YIPEGMQCSCGIDYYTPHE--ETNNESFVIYMF-VVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGK

General information: TITO was launched using: RESULT: Template: 1U19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -259915 for 2220 contacts (-117.1/contact) + 2D Compatibility (PS) -27460 + (NN) 385 + (LL) 2660 1D Compatibility (HY) -7600 + (ID) 700 Total energy: -292630.0 ( -131.82 by residue) QMean score : 0.214

(partial model without unconserved sides chains): PDB file : Tito_1U19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1U19-query.scw PDB file : Tito_Scwrl_1U19.pdb: