Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPR---EIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLR-QATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT 4BKZ Chain:A ((12-266)) ------------------------YELHETIGTG--AKVKLACHILTGEMVAIKIMDKNTL--------LPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCA-----------------------------SLAYAAPELIQG----GSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRG-KYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNR

General information: TITO was launched using: RESULT: Template: 4BKZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -166007 for 1738 contacts (-95.5/contact) + 2D Compatibility (PS) -23843 + (NN) -6313 + (LL) 2656 1D Compatibility (HY) -23600 + (ID) 4050 Total energy: -221157.0 ( -127.25 by residue) QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_4BKZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4BKZ-query.scw PDB file : Tito_Scwrl_4BKZ.pdb: