Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKRMIVRMTLPLLIVCLAFSSFSASARAASEEKYWDHWIERHAQPLDASNASNKDLRFLKKVLKGKRIVQLGETTHGAGEINATKVRMIKYLHEELGYDVLAFESGFPDTNASYLNMDQLTPKSTMKNSIYAVWHTEDVVELFDYMKEQKEKGDPLILTGF---DIQSMKNSFNVAAT--QWVKAVDPEKAELLSQSENDFSTLVTDSNTFDEFSQKKEKLVKNYQKLIKFTKTHASELKENLPKEPKAYEMFMHSLQLRIDVMETYMLEEMKEKLEEYPENIEDFSFFMRDRMMAEQFQWVADTLYPKKKIIVWGHNYHLRKQNTKMIKDWVQLNGPNMGDYLPERLKKQTYTIGIYAYSGASLDSSDNKTVKPVTSPPPSGSLEALLKAADRPAVFVDFLHTKNKKGTSWMYTPRTALYWGYMEEQMILKEQYDGVIWLEHITPSVIIK----------- 4B46 Chain:A ((1-367)) ---------MKLAMIGFGQAGGKVVDKFVEYDRERNAGIVRAAVAVNSA---KADLLGLKNIPKDQRVL-IGQSRVKGHGVGADNELGAEIAEEDIDEVQGAIDSIPVHEVDAFLVVSGLGGGTGSGGAPVLAKHLKRI------------YTEPVYGLGILPGSDEGGIYTLNAARSFQTFVREVD--------------NLLVFD---NDAWRKTGESVQGGYDEINEEIVNRFGVLFGSVVDSSEIINTLAGG-----GVSTVGYASEGVT-----AHTTNRITSLVRKAALGRLTLPCEIEGAERALLVLAGPPEHLNRKGIERGRKWIEEQTGSM-------------------------------EVRGGDYPIPG-------------------------------------------------AEKVAGVILLSGVTNVPRIKELQQVAIEAQD

General information: TITO was launched using: RESULT: Template: 4B46.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1951 -120670 -61.85 -384.30 target 2D structure prediction score : 0.49 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -61.85 2D Compatibility (Sec. Struct. Predict.) : 0.49 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.161

(partial model without unconserved sides chains): PDB file : Tito_4B46.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4B46-query.scw PDB file : Tito_Scwrl_4B46.pdb: