Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEQGTVKWFNAEKGFGFI--------ERENGDDVFVHFSAIQSDGFKSLDEGQKVSFDVEQGARGAQAANVQKA 4A76 Chain:A ((11-78)) ---GHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMEGFRSLKEGEPVEFTFKKSSKGFESLRV---

General information: TITO was launched using: RESULT: Template: 4A76.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 226 -38404 -169.93 -640.07 target 2D structure prediction score : 0.52 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -169.93 2D Compatibility (Sec. Struct. Predict.) : 0.52 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.658

(partial model without unconserved sides chains): PDB file : Tito_4A76.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4A76-query.scw PDB file : Tito_Scwrl_4A76.pdb: