Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------------------------------------MRRF-LLNVILVLAIVLFLR------YVHYSLEPE----------PSNQPDTYSNFSSLAENESPADYDISYNEKKGSKVLIMSPHGGRIEGGVSELVRYFNNEYSTYLFEGLKSHDNQTLHITSTNFDEPLAKKKIKEHQYVVAFHGYKGENKNTLVG------GTDRKRAKMIVRALERRGFSAEL----------ASSKSG-LAGLNAENINNQGETGLSIQLEISREQREAFFDDFYYKNRKYTKNSEFYAYVSAIKG---------VLEKEYS--- 4LDV Chain:A ((16-356)) SDALCRELWHACAGPLVTLPREGERVYYFPEGHMEQLEASMHQGLEQQMPSFNLPSKILCKVINIQRRAETDEVYAQITLLPELDQSEPTSPDAPVQETVHSFCKTLTASDTSTHGGFSVLRRHADDCL--PPLDMSQQPPWQELVAT-DLHNSEWHFRHIFRGQPRRHLLT-TGWSVFVSSKKLVAGDAFIFLRG---ENEELRVGVRRHMPSSVISSHSMHIGVLATAAHAITTGTIFSVFYKPRTSRSEFIVSVNRYLEAKTQKLSVGMRFKMRFKRFSGTIVGVQENKSSVWHDSEWRSLKVQWDEPSSVFRPERVSPWELEPLN

General information: TITO was launched using: RESULT: Template: 4LDV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 779 -57836 -74.24 -253.66 target 2D structure prediction score : 0.43 Monomeric hydrophicity matching model chain A : 0.63 3D Compatibility (PKB) : -74.24 2D Compatibility (Sec. Struct. Predict.) : 0.43 1D Compatibility (Hydrophobicity) : 0.63 QMean score : 0.186

(partial model without unconserved sides chains): PDB file : Tito_4LDV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4LDV-query.scw PDB file : Tito_Scwrl_4LDV.pdb: