Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLVYIGNGHYCYSNSTAMFLSSIGENVSPQLVEILTGVGLGAMIEYEKNLYFSMRDPDDGINYALNILGFTAEEHQQASDLDDPFPLLKQQIKQNPVILGPLDMG--ELTYHPNHK----NLNGSDHYVLGYQMDNE----NIYVQDPAGFPFVPLSLDQFKKAWMAERIPYRKGINKYWSTAKKVVTLDNNEIYERAIDYFKRTYRKFEKVDIGLIGREAICFYADQLLNAPITADTIRHTTFFLFQLSARRANDYAMYFKDRHSHLSVLKTEQAKVFGICHSMSVNKDWKGISEKLMKLADLEDNFRLELLKVGY 1DEU Chain:A ((138-203)) ------------------------------------------------------------------------------------REKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDGTEYWIVRNSWG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 1DEU.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 103 -5006 -48.60 -89.38 target 2D structure prediction score : 0.70 Monomeric hydrophicity matching model chain A : 0.52 3D Compatibility (PKB) : -48.60 2D Compatibility (Sec. Struct. Predict.) : 0.70 1D Compatibility (Hydrophobicity) : 0.52 QMean score : 0.499

(partial model without unconserved sides chains): PDB file : Tito_1DEU.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1DEU-query.scw PDB file : Tito_Scwrl_1DEU.pdb: