Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MGRHKATIEGLVMKERYYSHRAPGTERWITQPVCKVTRTEPIFEGYIDIEPIEIGGKVYIPGLNEYVIVTDRQRNIHNEWTYQTDRVIKTIIDEKSLKECEEHNNKKAKNNDTQNQRQIKTSWWQRLTKKD 3EDR Chain:D ((23-42)) ----------------YYSWRSPGRGSWFVQALCSI-----------------------------------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3EDR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 25 1480 59.20 74.00 target 2D structure prediction score : 0.35 Monomeric hydrophicity matching model chain D : 0.64 3D Compatibility (PKB) : 59.20 2D Compatibility (Sec. Struct. Predict.) : 0.35 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.435

(partial model without unconserved sides chains): PDB file : Tito_3EDR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3EDR-query.scw PDB file : Tito_Scwrl_3EDR.pdb: