Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------------------------------MNNIGEIISNFEGIIGALLGVIVTLILTHILKHFGQIKFYIVDFEIYFKTD-NDGWGTNVMPSKDEAKQIEIHSQIEIYNGAEIPKVLREIKFCFYKNTNLIVSVTPDDKATTEEFAEFGYYRDKLFNINLPSKQIIAINIIKFLNEKETKQVKKCNRVYLEAKDHNGKMYKVFLGEF------------------------------------------------------------------------------------------------------------------------------- 1R3E Chain:A ((1-309)) MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYK----DLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVG-------------EYDQVPPAYSAKKYKGERLYKLAREGKIINL-------PPKRVKIFKIWDVNIEG-------RDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKERVLTLRKVFNTR

General information: TITO was launched using: RESULT: Template: 1R3E.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 467 -7633 -16.34 -52.28 target 2D structure prediction score : 0.42 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -16.34 2D Compatibility (Sec. Struct. Predict.) : 0.42 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.152

(partial model without unconserved sides chains): PDB file : Tito_1R3E.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1R3E-query.scw PDB file : Tito_Scwrl_1R3E.pdb: