Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKVFIKALPVLRILIEA----GHQAYFVGGAVRDSYMKRTIGDVDIATDAAPDQVERLFQRTV----DVGKEHGTIIVLW-EDETYEVTTFRTESDYVDFRRPSEVQFISSLEEDLKRRDLTINAMAMTAD----GKVLDYFGGKKDIDQKVIRTVGKPEDRFQEDALRMLRAVRFMSQLGFTLSPETEEAIAKEK--SLLSHVSVERKTIEFEKLLQGRASRQALQTLIQTRLYEELPGFYHKRENLISTSEFP-F------FSLTSREELWAALL-INLGIVL-KDAPLFLKAWKLPGKVIKEAIHIADT-FGQS-------LDAMTMYRAGKKALLSAAK--ISQLRQNEKLDEKKLKDIQYAYQNLPIKSLKD-LDITGKDLLALRNRPAGKWVSEELQWIEQAVVTGKLSNQKKHIEEWLKTCGQH 3H38 Chain:A ((14-424)) --RVDPKILNLFRLLGKFGDEVNMPVYVVGGFVRDLLLGIKNLDIDIVVEGNALEFAEYAKRFLPGKLVKHDKFMTASLFLKGGLRIDIATARLEYYESPAKLPD-VE-MSTIKKDLYRRDFTINAMAIKLNPKDFGLLIDFFGGYRDLKEGVIRVLHT--LSFVDDPTRILRAIRFEQRFDFRIEETTERLLKQAVEEGYLERTTGPRLRQELEKILEEKNPLKSIRRMAQFDVIKHLFPKTYYTPSMDEKMENLFRNIPWVEENFGEVD-RFYAVLHVFLEFYDDESWKEVRDRYSLRRNLINEIRHVEKSAP-ALLEMLSERVPASFVYPLVKGVSNETICHFLAYLSG------EKEGLFKSY---LLKIKNTKLEKINGEYLIR-KGITSGKIIGEVLEKILMKKLDGDTRDEEEIL-EEVLASL--

General information: TITO was launched using: RESULT: Template: 3H38.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1749 31355 17.93 83.39 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.69 3D Compatibility (PKB) : 17.93 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.69 QMean score : 0.451

(partial model without unconserved sides chains): PDB file : Tito_3H38.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3H38-query.scw PDB file : Tito_Scwrl_3H38.pdb: