Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLGIDMNVKESVLCIRLTGELDHHTAETLKQKVTQSLEKDDIRHIVLNLEDLSFMDSSGLGVILGRYKQIKQIGGEMVVCAISPAVKRLFDMSGLFKIIRFEQSEQQALLTLGVAS 4HYL Chain:A ((3-114)) -ATDTQIRTEQGIDIITLHGHLDTRSSPAVQAAVLPRVTA--KGKMILDLREVSYMSSAGLRVLLSLYRHTSNQQGALVLVGVSEEIRDTMEITGFWNFFTACASMDEALRILGS--

General information: TITO was launched using: RESULT: Template: 4HYL.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 507 -100658 -198.54 -898.73 target 2D structure prediction score : 0.56 Monomeric hydrophicity matching model chain A : 0.79 3D Compatibility (PKB) : -198.54 2D Compatibility (Sec. Struct. Predict.) : 0.56 1D Compatibility (Hydrophobicity) : 0.79 QMean score : 0.491

(partial model without unconserved sides chains): PDB file : Tito_4HYL.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4HYL-query.scw PDB file : Tito_Scwrl_4HYL.pdb: