Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHIAGKRIWITGASGGLGERIAYLCAAEGAHVLLSARREDRLIEIKRKITEEWSGQCEI---FPLDVGRLEDIARVRDQIGSIDVLINNAGFGIFETVLDSTLDDMKAMFDVNVFGLIACTKAVLPQMLEQKKGHIINIASQAGKIATPKSSLYSATKHAVLGYSNALRMELSGTGIYVTTVNPGPIQTDFFSIADKGGDYAKNVGRWMLDPDDVAAQITAAIFTKKREINLPRLMNAGTKLYQLFPALVEKLAGRALMKK 3P19 Chain:D ((17-198)) ------KLVVITGASSGIGEAIARRFSEEGHPLLLLARRVERLKALN--LPNTLCAQVDVTDKYTFDTA----ITRAEKIYGPADAIVNNAGMMLLGQIDTQEANEWQRMFDVNVLGLLNGMQAVLAPMKARNCGTIINISSIAGKKTFPDHAAYCGTKFAVHAISENVREEVAASNVRVMTIAPSAVKTELLS--------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 3P19.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 914 -82748 -90.53 -462.28 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain D : 0.74 3D Compatibility (PKB) : -90.53 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.442

(partial model without unconserved sides chains): PDB file : Tito_3P19.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3P19-query.scw PDB file : Tito_Scwrl_3P19.pdb: