Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKKRMLDVLMLVIGAFFFALAVNLFAIPNDLGEGGVTGITLILYYLFQWSPGVTNFILNAFLLLIGYKFLDGKTTVYTIIAVAANSLFLHLTHGWSIPSDELIINTIFAGVFAGVGIGMIIRVGGTTAGSAILARIANKYLDWNISYALLFFDLIVVFSSYFIIGAEKMMFTIVMLY-IGTKVMDFIIEGLNTKKAITVISENKSEIAEQVNTLMDRGVTILSGKGNYTGQSKEILYIVINKQELSMLKKIIRSCDKKAFVIVHDVRDVFGEGFVDISK 1LKV Chain:X ((12-224)) DPVQLVNFLQ-------------------------SEHPQTIAVVLSYLDPPVAAQILGALPEELQTEVLKRIALLERTSPEVVKEIERNLEKKISGFVSRTFSKV-----------------GGIDTAAEIMNNL-------DRTTEKKIMDKLVQENPELADEIRRRMFVFEDILKLDDRSIQLVLREVDTRDLALALKGASDELKEKIFKNMS-----------------KRAAALLKDELEYMGPVRLKDVEEAQQKIINIIRRLEEAGEIVIAR

General information: TITO was launched using: RESULT: Template: 1LKV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain X - contact count / total energy / energy per contact / energy per residue : 556 -61915 -111.36 -292.05 target 2D structure prediction score : 0.50 Monomeric hydrophicity matching model chain X : 0.60 3D Compatibility (PKB) : -111.36 2D Compatibility (Sec. Struct. Predict.) : 0.50 1D Compatibility (Hydrophobicity) : 0.60 QMean score : 0.234

(partial model without unconserved sides chains): PDB file : Tito_1LKV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1LKV-query.scw PDB file : Tito_Scwrl_1LKV.pdb: