Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPSFDVVFVGHR-RGEVRSDNAMLGLLCDAAFDEL--TRPDVVIFPGGIGTR-TLIHDQTVLDWVREAHRHTLLTTSVCTG-GLVLAAAGLLNGLTATTHWRVQDLFNSLGARYV-PQRVVEHLPERVITAAGVSSGIDMGLRLVELLVSREAA-EASQLMIEYDPQPPVDAGSLAKASPATHRLALEFYQHRL 4K2H Chain:A ((32-188)) ---IDVETLACAESRAVVSY-HDIPMVADSTLSERQQALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPIASAAARVLGAHGLLKGRRYVCSGDLW---KAVPEGVYVDAPVVE--DGNLISGKGLGHVFDFALTLSARLLGDDAPVREQAEHIYYPW----------------------------

General information: TITO was launched using: RESULT: Template: 4K2H.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -89560 for 1117 contacts (-80.2/contact) + 2D Compatibility (PS) -16643 + (NN) -7755 + (LL) 2276 1D Compatibility (HY) -8800 + (ID) 1700 Total energy: -122182.0 ( -109.38 by residue) QMean score : 0.426

(partial model without unconserved sides chains): PDB file : Tito_4K2H.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4K2H-query.scw PDB file : Tito_Scwrl_4K2H.pdb: