Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKDKQFKEESSDLVYGLHAVTESLRANTGNKLYLQDDLRGKNVDKVKALATEKKVSISWTPKK-ILSDMTNGGVHQGFVLKVSEFAYADLSEIMTKAENEENPLILILDGLTDPHNLGSILRTADATNVTGIIIPKHRSVGVTPVVSKTSTGAVEHVPIARVTNLSQTLDTLKDKDFWIFGTDMNGTPSHKW---NTKGKLALVIGNEGKGISHNIKKQVDEMITIPMN----GHVQSLNASVAAAILMYEVFRNRL 2I6D Chain:A ((20-257)) ---KYRLREQAFAVEGPKLVGEMLPFYRCRMLVGTAAML-R------AVSTPHDAEVVELPESFDFKRISTQTTPQPLMAVFD-LPAEPEP--------VVEGLTLLLDGVQDPGNVGTILRTADWFGIRHVWLGTGSADVFSPKVVQASMGALARVQPTPLKNTVDTLAYFRRQGIPVYGAFLDGQSLYEAPLPNFTEPAILVLGSEGRGISPEVAAEITDRLTIPASGLSV---ESLNVAIATAILCSEWRRRS-

General information: TITO was launched using: RESULT: Template: 2I6D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -117217 for 1824 contacts (-64.3/contact) + 2D Compatibility (PS) -24351 + (NN) -5732 + (LL) 1524 1D Compatibility (HY) -10800 + (ID) 2950 Total energy: -159526.0 ( -87.46 by residue) QMean score : 0.458

(partial model without unconserved sides chains): PDB file : Tito_2I6D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2I6D-query.scw PDB file : Tito_Scwrl_2I6D.pdb: