Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MIIWINGAFGSGKTQTAFELHRRLN---P-SYVYDPEKMGFALRSMVPQEIAKDDFQSYPLWRAFNYSLLASLTDTYRGILIVPMTIVH-PEYFNEIIGRLRQEGRIVHHFTLMASKETLLKRLRTRAEGK-NSWAAKQIDRCVEGLSSP-IFEDHIQTDNLSIQDVAENIAARAELPLDPDTRGSLRRFADRLMVKLNHIRIK 2PEZ Chain:A ((6-176)) CTVWLTGLSGAGKTTVSMALEEYLVCHGIPCYTLDGD----NIRQGLNKNL-GFSPEDREENVRRIAEVAKLFADA-GLVCITS-FISPYTQDRNNARQIHEGASLPFFEVFVDAPLHVCEQRDVKGLYKKARAGEIKGFTGIDSEYEKPEAPELVLKTDSCDVNDCVQQVVELLQER--------------------------

General information: TITO was launched using: RESULT: Template: 2PEZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 811 -87221 -107.55 -531.83 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.61 3D Compatibility (PKB) : -107.55 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.61 QMean score : 0.504

(partial model without unconserved sides chains): PDB file : Tito_2PEZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2PEZ-query.scw PDB file : Tito_Scwrl_2PEZ.pdb: