Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MPYIILEDQTRLYYETHGS--GTPILFIHGVLMSGQFFHKQFSVLSANYQCIRLDLRGHGESDKVLHGHTISQYARDIREFLNAMELDHVVLAGWSMGAFVVWDYLNQFGNDNIQAAVIIDQSASDYQWEGWEHGPFDFDGLKTAMHAIQTDPLPFYESFIQNMFAEPP---AETETEWMLAEILKQPAAISSTILFNQTAADYRGTLQNINVPALLCFGEDKKFFSTAAGEHLRSNIPNATLVTFPKSSHCPFLEEPDAFNSTLLSFLDGVIGKS 3OM8 Chain:A ((8-265)) --FLATSDGASLAYRLDGAAEKPLLALSNSIGTTLHMWDAQLPALTRHFRVLRYDARGHGASSVPPGPYTLARLGEDVLELLDALEVRRAHFLGLSLGGIVGQWLALHA-PQRIERLVLANTSAWLGPAAQWDERI---AAVLQA-ED-MS---ETAAGFLGNWFPPALLERAEPVVERFRAMLMATNRHGLAGSFAAVRDTDLRAQLARIERPTLVIAGAYDTVTAASHGELIAASIAGARLVTLP-AVHLSNVEFPQAFEGAVLSFLG------

General information: TITO was launched using: RESULT: Template: 3OM8.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1506 -185731 -123.33 -734.11 target 2D structure prediction score : 0.69 Monomeric hydrophicity matching model chain A : 0.74 3D Compatibility (PKB) : -123.33 2D Compatibility (Sec. Struct. Predict.) : 0.69 1D Compatibility (Hydrophobicity) : 0.74 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_3OM8.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3OM8-query.scw PDB file : Tito_Scwrl_3OM8.pdb: