Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MMSNQTVYQFIAENQNELLQLWTDTLKELSEQESYQLTDQVYENISKEYIDILLLSVKDENAAESQISELALRAVQIGLSMKFLATALAEFWKRLYTKMNDKRLPDQESTELIWQIDRFFSPINTEIFNQYSISWEKTVSLQKIALQELSAPLIPVFENITVMPLVGTIDTERAKRIMENLLNGVVKHRSQVVLIDITGVPVVDTMVAHHIIQASEAVRLVGAKCLLAGIRPEIAQTIVNL-GIDLSQVITKNTLQKGIQTALEMTDRKIVSLGE 2VY9 Chain:A ((6-119)) -------------------------------------------------------------------------------------------------------------------------------------------------------PILKV-DDYWVVAIEETLHDQSVIQFKEELLHNITGVAGKGLVIDISALEVVDSFVTRVLIEISRLAELLGLPFVLTGIKPAVAITLT-EMGLDLRGMATALNLQKGLDKLKNLAR--------

General information: TITO was launched using: RESULT: Template: 2VY9.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 463 -111196 -240.16 -984.03 target 2D structure prediction score : 0.73 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -240.16 2D Compatibility (Sec. Struct. Predict.) : 0.73 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.616

(partial model without unconserved sides chains): PDB file : Tito_2VY9.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2VY9-query.scw PDB file : Tito_Scwrl_2VY9.pdb: