Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTNFILNENKQLSLAIEDENIENFYIDGTDLVRKIIRRSGSGVTSRVPVLSTQDLENKNLHELYDESWLRMKNRPNTELTTESINIADLFSGCGGLSLGVWEACRALGINP-RFSFACDLNEAALSVYEKNFSPDFSLNESIEKHINGEL-GAPLTVEEQRIKDKVKKIDFILAGPPCQGHSDLNNHTRR--KDPRNALLMRVSRVIELFQPSSVLVENVPGIIHDKSG-SFKEFKNHLKTQGYYFDEIVLNAEKLGVSQARRRYFIFASKTPVSSLNQINEFYS----------------------------TNSRPISWAISDLVENVGDDIFNT----------------------------ASEHSLENKRRIEYLFE---NNLFELPNSE------------RPDCH-------------------------------------------RLKPHSYKSVYGRMYWDRPAPTITRGFGST-GQGRFVHSLLKRTITPHEAARIQFFPDFFNFGDLRRRQYQDVIGNAVPSKLSYLLALHQLR 3SWR Chain:A ((537-996)) -------------------------------------------------------------------------------KLPKLRTLDVFSGCGGLSEGFHQA------GISDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSR-GQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQGFPDTYRLFGNILDKHRQ-VGNAVPPPLAKAIGLEIKL

General information: TITO was launched using: RESULT: Template: 3SWR.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 1851 -133141 -71.93 -391.59 target 2D structure prediction score : 0.54 Monomeric hydrophicity matching model chain A : 0.64 3D Compatibility (PKB) : -71.93 2D Compatibility (Sec. Struct. Predict.) : 0.54 1D Compatibility (Hydrophobicity) : 0.64 QMean score : 0.354

(partial model without unconserved sides chains): PDB file : Tito_3SWR.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3SWR-query.scw PDB file : Tito_Scwrl_3SWR.pdb: