Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MDDTDLQILSHLQRNGRLTMVELGKLVGLSSPSAAERVRKLEDKGVITGYSANICYEKLNKHVTAFILMEPKSCKH--YAAFATSHPDVAENHRITGMYSYVTKVVTESVHTLEDFIDTSMAHGKPTTLVVLSSSSCHPAF 2ZNY Chain:C ((25-142)) LDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLD-----------------------

General information: TITO was launched using: RESULT: Template: 2ZNY.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain C - contact count / total energy / energy per contact / energy per residue : 327 -57376 -175.46 -494.62 target 2D structure prediction score : 0.53 Monomeric hydrophicity matching model chain C : 0.73 3D Compatibility (PKB) : -175.46 2D Compatibility (Sec. Struct. Predict.) : 0.53 1D Compatibility (Hydrophobicity) : 0.73 QMean score : 0.453

(partial model without unconserved sides chains): PDB file : Tito_2ZNY.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2ZNY-query.scw PDB file : Tito_Scwrl_2ZNY.pdb: