Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAIIIAIIAAVIVIAALITFNVRNASPGPEKQEATDRIAPPEEEKNEAHYPAEARAAEHTPSVVKNDSPKEKR-DTMGDDIYRQALQKFKHSDEVHAEEEVTEESDKMQDRSYRDA-LLSMKNKKK 2DOQ Chain:D ((2-84)) -------------------------------------PLGSNEEANRFANQAKLRVQEAVFYIWSDKTLKYSQMANDEAESFRNTWLLFRSFQQWITLTQTFKEQSRLADQAFLNKMFRK------

General information: TITO was launched using: RESULT: Template: 2DOQ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain D - contact count / total energy / energy per contact / energy per residue : 26 2136 82.13 26.36 target 2D structure prediction score : 0.46 Monomeric hydrophicity matching model chain D : 0.62 3D Compatibility (PKB) : 82.13 2D Compatibility (Sec. Struct. Predict.) : 0.46 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.559

(partial model without unconserved sides chains): PDB file : Tito_2DOQ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2DOQ-query.scw PDB file : Tito_Scwrl_2DOQ.pdb: