Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAVIDDFEKLDIRTGTIVKAEEFPEAR-VPAIKLVIDFGTEIGIKQSSAQITKRYKPEGLINKQVIAVVNFPPRRIAGFKSEVLVLGGIPGQGDVVLLQPDQPVPNGTKIG 3G48 Chain:A ((4-112)) MANFEDFLTLDLRIGTVTHAEEFKEARVP-AIRLEIDFGEL-GMKQSSAQITKRYNPEDLIGQQIVAVVNFPPKRVAGFKSEVLVLGGVPEAGDVVLLQPNMELPNGTKIS

General information: TITO was launched using: RESULT: Template: 3G48.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 468 3034 6.48 28.09 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.88 3D Compatibility (PKB) : 6.48 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.88 QMean score : 0.501

(partial model without unconserved sides chains): PDB file : Tito_3G48.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3G48-query.scw PDB file : Tito_Scwrl_3G48.pdb: