Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSLLERLNQDMKLYMKNREKDKLTVVRMVKASLQNEAIKLKKDSLTEDEELTVLSRELKQ--RKDSLQEFSNANRLDLVDKVQKELDILEVYLPEQLS-EEELRTIVNETIAEVGAS-------SKADMGKVMGAIMPKVKGKADGSLINKLVSSQLS 3AL0 Chain:B ((369-480)) ------------------------------------------SKLTPQHFADLFKLMDEGKISIKIAKEIFP----EVFETGKMPSQIVEEKGLTQINDEKLIEELVKKAMEQNPKAVQDYKSGKKKAAGFFVGYVMRETKGKANPELTNRIIQKLLE

General information: TITO was launched using: RESULT: Template: 3AL0.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain B - contact count / total energy / energy per contact / energy per residue : 323 55011 170.31 539.32 target 2D structure prediction score : 0.74 Monomeric hydrophicity matching model chain B : 0.66 3D Compatibility (PKB) : 170.31 2D Compatibility (Sec. Struct. Predict.) : 0.74 1D Compatibility (Hydrophobicity) : 0.66 QMean score : 0.508

(partial model without unconserved sides chains): PDB file : Tito_3AL0.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3AL0-query.scw PDB file : Tito_Scwrl_3AL0.pdb: