Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MAKQLIQSEEEFKRIA--EQEGVFVFLKHSTTCPISQAAFHEFDAFANQHEDVPAYYLQVQEARPLSNFIAETYGVKHESPQIFIIQNGEVKWHTSHSQITEAAIEQHLS 1GH2 Chain:A ((2-103)) VGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQG----TAATNNISA-TPTFQFFRNKVRIDQYQ-G-ADAVGLEEKI-

General information: TITO was launched using: RESULT: Template: 1GH2.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 423 5608 13.26 56.08 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : 13.26 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.659

(partial model without unconserved sides chains): PDB file : Tito_1GH2.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1GH2-query.scw PDB file : Tito_Scwrl_1GH2.pdb: