Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MKHQNPSKRLLRLSIKYLLAAAAVVLT----YFAVIYILFSLAGTSYRSAAHVLLFAVVFLVLGLCFEPFERLMIHSFTFFKTGKRLFILLAGIVQLLFLWMTAHTTDQLISDIWLSTTEEMIVAAVFLILDKCNSALPS 1IXD Chain:A ((1-104)) GSSGSSGLAMPPGNSHGLEVGSLAEVKENPPFYGVIRWIGQPPGLNEV-------------LAGLELED-ECAGCTDGTF--RGTRYFTCALK--KALFVKLKSCRPDSRFASLQPSGPSSG------------------

General information: TITO was launched using: RESULT: Template: 1IXD.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 379 -21326 -56.27 -213.26 target 2D structure prediction score : 0.16 Monomeric hydrophicity matching model chain A : 0.58 3D Compatibility (PKB) : -56.27 2D Compatibility (Sec. Struct. Predict.) : 0.16 1D Compatibility (Hydrophobicity) : 0.58 QMean score : 0.246

(partial model without unconserved sides chains): PDB file : Tito_1IXD.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1IXD-query.scw PDB file : Tito_Scwrl_1IXD.pdb: