Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MEKEAFMEKLLSFMKEEAYKPLTVQELEEMLNITEAEEFKELVKALVALEEKGLIVRTRSDRYGIPEKMNLIKGKISAHAKGFAFLLPEDTSLSDVFIPPNELNTAMNGDIVMVRLNSQSSGSRQEGTVIRILERAIQRVVGTYTETRNFGFVIPDDKKITSDIFIPKNGKNGAAEGHKVVVKLTSYPEGRMNAEGEVETILGHKNDPGIDILSVIHKHGLPGE----FPADAMEQASSTPDTIDEK-DLKDRRDLRDQVIVTIDGADAKDLDDAVTVTKLDDGSYKLGVHIADVSHYVTENSPIDKEALERGTSVYLVDRVIPMIPHRLSNGICSLNPKVDRLTLSCEMTINSQGQVTEHEIFQSVIKTTERMTYSDVNKILVDDDEELKQKYEPLVPMFKDMERLAQILRDKRMDRGAVDFDFKEAKVLVDDEGAVKDVVIRERSVAEKLIEEFMLVANETVAEHFHWMNVPFIYRIHEEPNAEKLQKFLEFVTTFGYVVKGTAGNIHPRALQSILDAVRDRPEETVISTVMLRSMKQAKYDPQSLGHFGLSTEFYTHFTSPIRRYPDLIVHRLIRTYLINGKVDEATQEKWAERLPDIAEHTSSMERRAVDAERETDDLKKAEYMLDKIGEEFDGMISSVTNFGMFVELPN-TIEGLVHVSFMTDDYYRFDEQHFAMIGERTGNVFRIGDEITVKVVDVNKDERNIDFEIVGMKGTPRRPRELDSSRSRKRGKPARKRVQSTNTPVSPAPSEEKGEWFTKPKKKKKKRGFQNAPKQKRKKKK 2R7D Chain:A ((21-462)) -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RADKSRVLRDLKLPETPEA-AHALLLRLGVWDEARTPYADRLRAALNAVELPVPDFDPAEERLDLTHLPTFAIDDEGNQDPDDAVGVEDLGGGLTRLWVHVADVAALVAPDSPLDLEARARGATLYLPDRTIGMLPDELVAK-AGLGLHEVSPALSICLDLDPDGNAEAVDVLLTRVK-VQRLAYQEAQARLEAGE-----------EPFVTLARLARASRRLREGEGALSIDLPEVRVKADETGAS--VFPLPKPEMRTVVQECMTLAGWGTAIFADDNEIPLPFATQDYPTREVAGD----------------------TLPA--------------MWARRKTLARTRFQPSPGPHHGMGLDLYAQATSPMRRYLDLVVHQQLRAFLAGRDP------LSSKVMAAHIAESQMNADATRQAERLSRRHHTLRFIAAQPERVWDAVVVDRRGAQATLLIPDLAFDVQVN------------------------TPAAPGTALQVQFADIDLPQMRVRARSVL----------------------------------------------------------------------

General information: TITO was launched using: RESULT: Template: 2R7D.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2304 83279 36.15 191.01 target 2D structure prediction score : 0.60 Monomeric hydrophicity matching model chain A : 0.65 3D Compatibility (PKB) : 36.15 2D Compatibility (Sec. Struct. Predict.) : 0.60 1D Compatibility (Hydrophobicity) : 0.65 QMean score : 0.437

(partial model without unconserved sides chains): PDB file : Tito_2R7D.pdb: (Unconserved sides chains are recalculated) : Sequence: align-2R7D-query.scw PDB file : Tito_Scwrl_2R7D.pdb: