Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDPNGVIYWKGSYHVFFQWQPFQTGHG-AKFWGHYTTQDVVNWKREEIALAPSDW-FD-KNGCYSGSAVTK---------DD--RLYLFYTGNVRDQD--------GNRETYQCLAVSDD-GLSFEKKG---VVAR-LPEG---YTAHFRDPKVWEHE--GTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYMWECPDLFSLQ------GSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHG---------EFTELDQGFDFYAPQTLEDD-QGRRILFAWMAVPDQDEGSHPTIDCHWIHCMTLPRQLTLS-GQ---KLIQQPLPELKAMRRNEKKIH-INMHGSSGALPV-EKPERTEILLE-DIH-TESGFSISIRGT------ATFSFHKDEGIVTLERKSFDG-KRT----EAR--HCRI--KDLHTVHMFLDASSVEIFINNGEEVLSARYFPFPGNHEVTASATGK--SEMNVGIWTLM 1Y4W Chain:A ((3-514)) -----------------------YDQPYRGQYHFSPQKNWMNDPNGLLYHNGTYHLFFQYNPGGIEWGNI-SWGHAISEDLTHWEEKPVALLARGFGSDVTEMYFSGSAVADVNNTSGFGKDGKTPLVAMYTSYYPVAQTLPSGQTVQEDQQSQSIAYSLDDGLTWTTYDAANPVIPNPPSPYEAEYQNFRDPFVFWHDESQKWVVVTSIAE---LHKLAIYTSDNLKDWKLVSEFGPY-----NAQGGVWECPGLVKLPLDSGNSTKWVITSGLNPGGPPG---TVGSGTQYFVGEFDGT--TFTPDADTVYPGNSTANWMDWGPDFYAAAGYNGLSLNDHVHIGWMNNWQYGA-NIP--TYPWRSAMAIPRHMALKTIGSKATLVQQPQEAWSSISNKRPIYSRTFKTLSEGSTNTTTTGETFKVDLSFSAKSKASTFAIALRASANFTEQTLVGYDFAKQQIFLDRTHSGDVSFDETFASVYHGPLTPDSTGVVKLSIFVDRSSVEVFGGQGETTLTAQIFPSSDAVHARLASTGGTTEDVRADIYKIA

General information: TITO was launched using: RESULT: Template: 1Y4W.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 2486 59070 23.76 134.55 target 2D structure prediction score : 0.64 Monomeric hydrophicity matching model chain A : 0.71 3D Compatibility (PKB) : 23.76 2D Compatibility (Sec. Struct. Predict.) : 0.64 1D Compatibility (Hydrophobicity) : 0.71 QMean score : 0.521

(partial model without unconserved sides chains): PDB file : Tito_1Y4W.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1Y4W-query.scw PDB file : Tito_Scwrl_1Y4W.pdb: