Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence ------------------MQQACIAIIIIL-----LTVAAYLAMVKLYKR-FPLPFLIPVLTT-TILIVAALMMFHVSYEGYMIGGKWINSLLGPAVVALAYPLYKQWHIIVKHCVPIL-GGVLVGLCMGMISGLIFAEAFGIDHDLLLSIL-PKSITTPVAIQIAAGLGGVPSMTVVFVMIAGFSGVI-L-GPL-FLKWLRIRSSLGQGIALGSASH-ALGTSKALEYGELAVSMSSVSMT-LCAVLGSFFGPLVVWLFHI 3WOZ Chain:A ((645-869)) TEDVAEVLNRCASSNWSERKEGLLGLQNLLKNQRTLSRIELKRLCEIFTRMFADPH--GKVFSMFLETLVDFIQVHKDD-------------LQDWLFVLLTQLLKK------------MGADLLGSVQAKVQKALDITRESFPNDLQFNILMRFTVDQT----------QTPSLKVKVAILKYIETLAKQMDPRDFTNSSETRLAVSRVITWTTEPKSSDVRKAAQSVLISLFELNTPEFTMLLGALPKTFQDGATKLLHN

General information: TITO was launched using: RESULT: Template: 3WOZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 780 -44928 -57.60 -232.78 target 2D structure prediction score : 0.59 Monomeric hydrophicity matching model chain A : 0.62 3D Compatibility (PKB) : -57.60 2D Compatibility (Sec. Struct. Predict.) : 0.59 1D Compatibility (Hydrophobicity) : 0.62 QMean score : 0.297

(partial model without unconserved sides chains): PDB file : Tito_3WOZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-3WOZ-query.scw PDB file : Tito_Scwrl_3WOZ.pdb: