Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence --MVYQTKRDVPVTLMIVFLIL------------------LIQADAIVP----FVLGNMRVSGWIIFILLTLLNGLIIW-------------SFIDLKYVLKE-HHLIIKAGLIKHQIPYENIDKVVQKKKLWSGFRLIGSRHA---------ITIYYQGGWGHAVISPQKSEEFIHKLKEKNS-NIIIFTKSK 4OMV Chain:A ((0-202)) AMLLYTKKDDIYSDIVRMILLIKGANAKIVDVSKEENSKHLEELNIITPNGNIPTLSTDDFAVYRLSVIIEAIEDLYPFPPMFPVFPKQRANARILLEYVNKTFLQNIIKLQSPDLDEKQANEIKMLMQRDIISTYKKIVSERAQNINVLTLIITFVFYYFIKLKISIPTKDKNIIKEIKELLSEPNFIKTIKA

General information: TITO was launched using: RESULT: Template: 4OMV.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output Monomeric PKB - chain A - contact count / total energy / energy per contact / energy per residue : 460 -23425 -50.92 -160.45 target 2D structure prediction score : 0.58 Monomeric hydrophicity matching model chain A : 0.68 3D Compatibility (PKB) : -50.92 2D Compatibility (Sec. Struct. Predict.) : 0.58 1D Compatibility (Hydrophobicity) : 0.68 QMean score : 0.282

(partial model without unconserved sides chains): PDB file : Tito_4OMV.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4OMV-query.scw PDB file : Tito_Scwrl_4OMV.pdb: