Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence -------MADIPYG------TDYPDAPWIDRDGHVLIDDGGK-PTQVHRGQARIAYRLAERYQ----DKLLHVAGIGWHSW-----DGRRWAADDR--GEAKRAVLAELRQALSDSLNDKELRADVRKCESASGVAG-----VLDLAAALVPFAATVADLDSDPHLLNVANGTLDLHTLKLR----PHAPADRITKICRGAYQSDTESPLWQAFLTRVLPDEGVRGFVQRLA--------------G-VGLLGTVREHVLAILIGVGANGKSVFDKAIRYA-------LGDYACTAEPDLFMHRENAHPTGEMDLRGVRWVAVSE-SEKD----RRLAESTIKRLTGGDTIRARKMRQDFVEFT-PSHTPLLITNHLPRVPGDD---------------TAIWRRI-RVVPFEVVI--PADEQDRELDARL-----QLEA-------DSILSWA-VAGWSDYQRIGLSQP------DAVLAATSNYR-----EDSDTIKRFIDDECVTSSPVLKATTTHLFEAWQRW-----RVQEGVPEISRKAFGQSLDTHGYPVTDKARD----------GRWRAGIAVRGADDFDD-- 4YCZ Chain:B ((314-1176)) SEYRYAALAKDAYQQMGTAPVTEPPQVILGTEDLLSRLYDEKMDDTLATAAAQLAALWREHVDETPFEKANYLANLALQIHHPLPQTLFRWLNEYHMYGSQVDDILRHRPSPACHSLFWQAVFIALKVGDAARLLDQAGWGHVYAYVNVQRAVDETIAVLESCPTLFRVRARGLLEHLRRFAEGWEIYENLNIVFDIVLGQQGAILEAA--QDWLEATVGLANSESYLDRLARAFHTAVESDFVEIGMACVFEDNIKGVIGLLRGWSLPIAAAVAEIASLGKWLEVDGIKDSTLVQYAQALADYEGLSSVQDRDGWELSISVLGRMPERSEEMVRDLVEHLVQQLHVDSNATVDRLWFLLNELGMIEFAEDTTETYGDILARDSHRYGEAMWYYALAHRPNKVREVMNLLTSYSLIQPPANDLDDYLYKLLNDRKNTLEQCASQDMEAAELLGKMLSGYASLRQFYDIRPHATPLSRRKQAATALISVIASSDDEDFLLALLGEALVFVSDPTLDQIDVLLKAIEDLQAVGSRVYNACDEFLQLVLASAPGGSSLVASQLQRSLSGTGGEDIMRRLRLGLAKDLAGLWLAEA

General information: TITO was launched using: RESULT: Template: 4YCZ.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) 38736 for 2763 contacts (14.0/contact) + 2D Compatibility (PS) -46325 + (NN) -1540 + (LL) 332 1D Compatibility (HY) 18000 + (ID) 2000 Total energy: 7203.0 ( 2.61 by residue) QMean score : 0.087

(partial model without unconserved sides chains): PDB file : Tito_4YCZ.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4YCZ-query.scw PDB file : Tito_Scwrl_4YCZ.pdb: