Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPR---ELSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQIAGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFGRQAHGYPDLSTTYCGSAAYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRGVLYPEGLELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG 4CQG Chain:A ((11-263)) -----------YELYETIGTGGFAKVKLACHVLTGEMVAIKIMDKNALGSD-----LPRVKTEIDALKSLRHQHICQLYHVLETKN-KIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQILSAVAYVHSQGYAHRDLKPENLLFD-ENHKLKLIDFGLCAK-----------CGSLAYAAPELIQG-----SEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGK-YEVPKWLSPSSILLLQQMLQVDPKKRISMRNLLNHPWVMQDYSC

General information: TITO was launched using: RESULT: Template: 4CQG.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -132924 for 1788 contacts (-74.3/contact) + 2D Compatibility (PS) -25386 + (NN) -14061 + (LL) 908 1D Compatibility (HY) -24000 + (ID) 4450 Total energy: -199913.0 ( -111.81 by residue) QMean score : 0.537

(partial model without unconserved sides chains): PDB file : Tito_4CQG.pdb: (Unconserved sides chains are recalculated) : Sequence: align-4CQG-query.scw PDB file : Tito_Scwrl_4CQG.pdb: