Modeling by threading (Tito software) Unconserved sides chains calculation (Scwrl software) Evaluation (QMean software) Input alignment information: Query sequence MLESLKTIVKTNSDK-KLFDGDLQVSYGEFYNLVRQDM------ASQDNRKHVISTHSLLNQLVRFVSKLCQKALPIICKPNLTHNEISRLEKE--------------------------------------------------------VQYAPQLADFGVLSSGTTADAKLLWRSFASWSDFFSIQNAYFSVTSNSRLFIQGDFSFTGNLN--LVLSLLLLGGTLVVTQKNSVKYWQTLWEKTGVTHLYLLPSYLKLVEQYSK---ETALDNKTIITSSQYVSDSLLEGLYIKHPKVSVKIFYGASELNYVSWYDGRDIRDKPQYVGEIVPN-VAVRIKE-----------GRIFVKTPYSICGL-------------SSEYCAGDYGELI-DGKLYLFGRGDDWCNQSGIKLYLPRLIEKIKTCPYIKDAVAFTKESQSHGQESHCCIVLIEN-QMQQECLKWLSEH-FEKKYGFKHYHIVSKIPLMPSGKIDYQQLKRQLA 1MDB Chain:A ((28-529)) -GDLLRDRAAKYGDRIAITCGNTHWSYRELDTRADRLAAGFQKLGIQQKDRVVVQLPNIKEFFEVIFALFRLGALPVFALPSHRSSEITYFCEFAEAAAYIIPDAYSGFDYRSLARQVQSKLPTLKNIIVAGEAEEFLPLEDLHTEPVKLPEVKSSDVAFLQLSGGSTGLSKLIPRTHDDYIYSLKRSVEVCWLDHSTVYLAALPMAHNYPLSSPGVLGVLYAGGRVVLSPSPSPDDAFPLIEREKVTITALVPPLAMVWMDAASSRRDDLSSLQVLQVGGAKFSAEAARRVKAVF-GCTLQQVFGMAEGLVNYTRLDDPEEIIVNTQGKPMSPYDESRVWDDHDRDVKPGETGHLLTRGPYTIRGYYKAEEHNAASFTEDGFYRTGDIVRLTRDGYIVVEGRAKDQINRGGEKVAAEEVENHLLAHPAVHDAAMVSMPDQFLGERSCVFIIPRDEAPKAAELKAFLRERGLAAYKIPDRVEFVESFPQTGVGKVSKKALREAIS

General information: TITO was launched using: RESULT: Template: 1MDB.pdb Alignment : align.pir Tito was launched with SMD and SCWRL Tito text output 3D Compatibility (PKB) -218591 for 3498 contacts (-62.5/contact) + 2D Compatibility (PS) -44131 + (NN) -18182 + (LL) 68 1D Compatibility (HY) -6800 + (ID) 3650 Total energy: -291286.0 ( -83.27 by residue) QMean score : 0.474

(partial model without unconserved sides chains): PDB file : Tito_1MDB.pdb: (Unconserved sides chains are recalculated) : Sequence: align-1MDB-query.scw PDB file : Tito_Scwrl_1MDB.pdb: